engleski

Satellite DNA and centromere evolution

Based on structural and evolutionary studies it is proposed that satellite DNAs are highly evolved sequences whose evolution has proceeded through the combined action of natural selection and molecular drive. Their recruitment to a satellite library and retention within the genome could be related to some structural characteristics which enable them to be extended into a functional centromere array. A newly formed array could replace the previous centromere if it has some selective advantage in transmission at meiosis due to particular satellite sequence features and/or high homogeneity.

satellite DNA; transcription; centromere

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