engleski

Modelling of Epitope-Paratope Interaction Using Molecular Recognition theory

We investigated the modelling of epitope-paratope interactions using Molecular Recognition Theory. It is shown that the standard algorithm according to Kyte and Doolittle may be combined with complex methods of the secondary structure prediction to extract the information relevant for the epitope location and modelling. Described concept represents useful and simple set of procedures for deriving new biologically active peptides and antibodies and also performing modulation of peptide-receptor interaction.

modelling; epitope; paratope; interactions; molecular; recognition

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