The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis (CROSBI ID 202007)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Revilla-i-Domingo, Roger ; Bilić, Ivan ; Vilagos, Bojan ; Tagoh, Hiromi, Ebert, Anja ; Tamir, Ido ; Smeenk, Leonie ; Trupke, Johanna ; Sommer, Andreas ; Jaritz, Markus ; Busslinger, Meinrad
engleski
The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis
Pax5 controls the identity and development of B cells by repressing lineage-inappropriate genes and activating B-cell-specific genes. Here, we used genome-wide approaches to identify Pax5 target genes in pro-B and mature B cells.
B-cell identity
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Podaci o izdanju
Povezanost rada
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Biologija
