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Tumor Necrosis Factor-Alpha in Peripical Tissue Exudates of Teeth with Apical Periodontitis (CROSBI ID 137164)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Pezelj-Ribarić, Sonja ; Magašić, Karolina ; Prpić, Jelena ; Miletić, Ivana ; Karlović, Zoran Tumor Necrosis Factor-Alpha in Peripical Tissue Exudates of Teeth with Apical Periodontitis // Mediators of inflammation, 2007 (2007), 69416; 1-4-x

Podaci o odgovornosti

Pezelj-Ribarić, Sonja ; Magašić, Karolina ; Prpić, Jelena ; Miletić, Ivana ; Karlović, Zoran

engleski

Tumor Necrosis Factor-Alpha in Peripical Tissue Exudates of Teeth with Apical Periodontitis

Aim. The aim of this study was to determine tumor necrosis factor-alpha (TNF-&#945; ) levels in periapical exudates and to evaluate their relationship with radiological findings. Methodology. Periapical exudates were collected from root canals of 60 single-rooted teeth using absorbent paper points. TNF-&#945; levels were determined by enzyme-linked immunosorbent assays. The samples were divided into three groups according to the periapical radiolucent area. Results. Nonparametric Kruskal-Wallis test revealed significant differences between TNF-&#945; concentrations in control group (40, 57&plusmn ; ; ; ; ; ; 28, 15 pg/mL) and group with larger radiolucent areas (2365, 79&plusmn ; ; ; ; ; ; 582, 95 pg/mL), as well as between control and canals with small radiolucent areas (507, 66&plusmn ; ; ; ; ; ; 278, 97) (P<.05). Conclusions. The levels of TNF-&#945; increase significantly in teeth with periapical pathosis, from smaller to bigger lesions. This research and its results have shown that objective analysis of the TNF-&#945; levels enables establishment of a relationship between different concentrations of TNF-&#945; and different radiological changes.

tumor necrosis factor-alpha; periapical exudates

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Podaci o izdanju

2007 (69416)

2007.

1-4-x

objavljeno

0962-9351

Povezanost rada

Dentalna medicina

Indeksiranost