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izvor podataka: crosbi

Comparison of different root canal sealers: cytotoxicity and the type of induced cell death (CROSBI ID 154142)

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Brzović, Valentina ; Miletić, Ivana ; Anić, Ivica ; Vuković, Lidija ; Kqiku, Lumnije ; Osmak, Maja Comparison of different root canal sealers: cytotoxicity and the type of induced cell death // Stomatologie, 106 (2009), 47-51. doi: 10.1007/s00715-009-0089-6

Podaci o odgovornosti

Brzović, Valentina ; Miletić, Ivana ; Anić, Ivica ; Vuković, Lidija ; Kqiku, Lumnije ; Osmak, Maja

engleski

Comparison of different root canal sealers: cytotoxicity and the type of induced cell death

The aim of this study was to compare in vitro cytotoxicity and determine the type of cell death induced by Hermetic, Diaket, GuttaFlow, Epiphany, SuperEBA and IRM using human laryngeal carcinoma HEp2 cells as the model system. The cytotoxicity was determined by counting the total number of cells by electronic counter, while the number of viable cells was estimated under a light microscope. The number of apoptotic or necrotic cells was estimated under a fluorescent microscope according to their characteristic morphology and staining with specific fluorescent dyes. The results show that GuttaFlow was biocompatible, hardly reducing the number of living human laryngeal carcinoma HEp2 cells thorough all research periods(except after one month period). Different from that, Diaket, Epiphany, IRM, Hermetic, and Super EBA exhibited strong toxicity. Diaket and IRM mostly induced apoptosis while for Epiphany, Hermetic and Super EBA, necrosis was the predominant or only type of cell death.

Apoptosis ; cytotoxicity ; necrosis ; root canal

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Podaci o izdanju

106

2009.

47-51

objavljeno

0946-3151

1613-7698

10.1007/s00715-009-0089-6

Povezanost rada

Dentalna medicina

Poveznice
Indeksiranost