engleski

Development of an ion chromatographic method for determination of inorganic anions in surface water by using computer assisted gradient optimization methodology

This work focuses on computer assisted gradient elution method development in inorganic anion analysis of surface water using ion chromatography. Integral elution model was applied to model gradient retention behavior based on isocratic experimental information. Applied optimization strategy incorporates in-house developed elimination criteria for optimal condition search routine with gradient retention modeling resulting in baseline separation within satisfactory run time. The reliability of developed method was extensively tested by performing performance characteristics evaluation process. Based on evaluation result it can be stated that developed method shows more than satisfactory performance characteristics proving that applied computer assisted method development process is very useful alternative when surface water which differs in composition significantly has to be analyzed in the limited time frame.

ion chromatography ; surface water ; computer assisted method development

nije evidentirano