Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi !

Određivanje interferona gama ex vivo u zdravstvenih radnika (CROSBI ID 599064)

Prilog sa skupa u časopisu | sažetak izlaganja sa skupa

Dodig, Slavica ; Zrinski Topić Renata ; Živčić, Jadranka ; Pavić, Ivan Određivanje interferona gama ex vivo u zdravstvenih radnika // Biochemia medica. 2012. str. A20-A20

Podaci o odgovornosti

Dodig, Slavica ; Zrinski Topić Renata ; Živčić, Jadranka ; Pavić, Ivan

engleski

Određivanje interferona gama ex vivo u zdravstvenih radnika

Detection and follow-up the blood test determining interferon-gamma (IFN-γ) released from effector T-lymphocytes (interferon-gamma release assay, IGRA) upon stimulation with M. tuberculosis specific peptides should be performed in subjects at an increased risk of M. tuberculosis infection such as health care workers (HCW) in chest hospital and immunocompromised subjects. Two cases of HCW with type 1 diabetes mellitus (T1DM) and positive anti-thyroglobulin (anti-Tg) autoantibodies, respectively, are presented. Case 1: a 46 year-old female HCW who has been having T1DM for 20 years underwent routine screening for Latent tuberculosis infection (LTBI). She was not acutely ill, she had normal body temperature, was eupneic and lung auscultation show normal breathing. Tuberculin skin test (TST) was negative and IGRA was positive (4.7 kIU/L). Positive IGRA indicated the LTBI, while TST result was false negative. Antituberculosis prophilaxis was not used. Case 2: a 57 year-old clinically healthy female was included in an annual screeding for LTBI. Initial testing showed positive TST and IGRA (5.2 kIU/L) and elevated levels of anti-Tg (86.4 kIU/L). She was free from acute disease, afebrile, eupneic, with normal breath sounds on auscultation. One year later IGRA was still positive. Antituberculosis prophilaxis was not used. Although isoniazid prophylaxis was not used in these subjects, tuberculosis did not develop during the 4-year follow-up period.

interferon gamma; IGRA-test; latent tuberculosis infection; health care workers

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o prilogu

A20-A20.

2012.

nije evidentirano

objavljeno

Podaci o matičnoj publikaciji

Biochemia medica

Zagreb: Medicinska naklada

1330-0962

Podaci o skupu

23rd Symposium Croatian Society for Medical Biochemistry and Laboratory Medicine. Tuberculous infection – continuous challenge

predavanje

22.09.2012-22.09.2012

Zagreb, Hrvatska

Povezanost rada

Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita, Farmacija

Indeksiranost