MICROBIAL ETHANOL PRODUCTION IN POST-MORTEM URINE SAMPLE (CROSBI ID 599172)
Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
NESTIĆ, Marina ; KOVAČIĆ, Zdravko ; GUSIĆ, Stjepan ; MLINAREK, Tajana ; SARDELIĆ, Sanda ; SALAMUNIĆ, Ilza ; SUTLOVIĆ, Davorka
engleski
MICROBIAL ETHANOL PRODUCTION IN POST-MORTEM URINE SAMPLE
We present a case in which post-mortem blood ethanol concentration was 0.02 g kg-1 and acetone concentration was 0.51 g kg-1 while urine ethanol concentration was 6.0 g kg-1 and acetone concentration was 0.63 g kg-1. The presence of acetone in blood and urine indicated the presence of ketoacidosis, which can lead to ketotic diabetic coma. The concentrations acetone may reach in diabetics are almost independent from the post-mortem interval. Sodium fl uoride was not added to the urine sample in which we continued to observe a remarkable increase in isopropyl alcohol concentration. The result was not logical and suggested that the alcohol concentration in urine was not due to consumption of alcoholic beverages. External contamination was excluded. Glucose levels were determined a few days after blood and urine samples were collected. Species of bacteria and yeasts, including Candida albicans, were isolated from both samples. A few days after the autopsy, we received the information that the patient suffered from Diabetes Mellitus and did not receive insulin therapy regularly. To prevent post-mortem ethanol production and thus making wrong assumptions of the cause of death, it is necessary to add sodium fl uoride in blood and urine samples from patients with diabetes.
ethanol and acetone concentrations in blood and urine; ketoacidosis; prevention of post-mortem ethanol production; sodium fl uoride
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Podaci o prilogu
48-48.
2012.
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objavljeno
Podaci o matičnoj publikaciji
Arhiv za higijenu rada i toksikologiju
Želježić, Davor
0004-1254
Podaci o skupu
Croatian Congress of Toxicology (CROTOX) 2012
poster
02.10.2012-05.10.2012
Primošten, Hrvatska
Povezanost rada
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Farmacija