Trace elements and inflammatory and oxidative markers in hemodialysis patients (CROSBI ID 602855)
Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Jurasović, Jasna ; Mujagić, Renat ; Sekovanić, Ankica ; Vrkić, Nada ; Orct, Tatjana
engleski
Trace elements and inflammatory and oxidative markers in hemodialysis patients
Oxidative stress, inflammation and trace element imbalance occur in most hemodialysis (HD) patients. In order to test trace element status and the possible influence of inflammatory state and oxidative stress in HD patients on biomarkers in plasma and erythrocytes, we assessed related parameters in 100 HD patients. They included: Fe, Cu, Zn, and Se levels in plasma and erythrocytes, total and non-transferrin Fe, ferritin, C- reactive protein, albumin/globulin, ceruloplasmin, protein carbonylation and superoxide dismutase. Plasma Fe and Cu markers were clearly affected by inflammatory state and oxidative stress, while erythrocyte concentrations remained unaffected. HD patients showed Zn and Se deficiency and apparently normal Fe and Cu plasma levels. In HD patients, Fe and Cu plasma level was not a reliable marker of body status. Using erythrocytes as a marker of trace element status should be evaluated, especially in relation to the role of Fe (indirectly of Cu, as well) for efficient anemia treatment in HD patients.
biomarkers; essentail elements; chronic hemodyalisis patients; inflammation; oxidatative stress
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Podaci o prilogu
40-40.
2013.
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objavljeno
Podaci o matičnoj publikaciji
Journal of trace elements in medicine and biology
0946-672X
Podaci o skupu
ISTERH Conference "Trace Element Research on Health and Diseases" (10 ; 2013)
poster
18.11.2013-22.11.2013
Tokyo, Japan
Povezanost rada
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita, Farmacija