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Nanotherapeutics in the EU : an overview on current state and future directions (CROSBI ID 210456)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Hafner, Anita ; Lovrić, Jasmina ; Perina Lakoš, Gorana ; Pepić, Ivan Nanotherapeutics in the EU : an overview on current state and future directions // International journal of nanomedicine, 9 (2014), 1; 1005-1023. doi: 10.2147/IJN.S55359

Podaci o odgovornosti

Hafner, Anita ; Lovrić, Jasmina ; Perina Lakoš, Gorana ; Pepić, Ivan

engleski

Nanotherapeutics in the EU : an overview on current state and future directions

The application of nanotechnology in areas of drug delivery and therapy (ie, nanotherapeutics) is envisioned to have a great impact on public health. The ability of nanotherapeutics to provide targeted drug delivery, improve drug solubility, extend drug half- life, improve a drug’s therapeutic index, and reduce a drug’s immunogenicity has resulted in the potential to revolutionize the treatment of many diseases. In this paper, we review the liposome-, nanocrystal-, virosome-, polymer therapeutic-, nanoemulsion-, and nanoparticle-based approaches to nanotherapeutics, which represent the most successful and commercialized categories within the field of nanomedicine. We discuss the regulatory pathway and initiatives endeavoring to ensure the safe and timely clinical translation of emerging nanotherapeutics and realization of health care benefits. Emerging trends are expected to confirm that this nano-concept can exert a macro-impact on patient benefits, treatment options, and the EU economy.

nanotechnology ; drug delivery ; EU approval procedures ; EU marketed products

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Podaci o izdanju

9 (1)

2014.

1005-1023

objavljeno

1176-9114

1178-2013

10.2147/IJN.S55359

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