engleski

Arterial stiffness indices in aggressive periodontitis patients

Background The exposure to inflammatory periodontal disease represents a risk factor for the development of atherosclerosis. The aim of this research was to assess the relationship between carotid elastic properties and periodontal condition in patients with aggressive periodontitis. Methods The study was conducted on 30 subjects with untreated aggressive periodontitis (test group, 13 men and 17 women, mean age 34.7±6.3 years) and 34 periodontal healthy volunteers (control group, 15 men and 19 women, mean age 27.7±5.7 years). Periodontal parameters were assessed in terms of clinical attachment level using a periodontal probe. Arterial stiffness measurements on common carotid artery (CCA) were performed using Aloka ProSound ALPHA 10 with 13 MHz linear probe. Results In comparison with the control group, test group showed statistically significant difference (p<0.05) in the mean beta stiffness (9.4 vs. 6.7), compliance (0.85 vs. 0.99), and pulse wave velocity (6.6 vs. 5.4) when measured on right CCA only. Test group also showed statistically significant difference (p<0.05) in the mean beta stiffness (8.3 vs. 6.5), elastic modulus (98.5 vs. 83.0), compliance (0.87 vs. 0.99), and pulse wave velocity (6.2 vs. 5.4) when measurements were observed for both CCA. No statistically significant differences were found among groups regarding intima media thickness (p>0.05). Conclusion The present results demonstrate that aggressive periodontitis may affect carotid artery hemodynamics, despite normal intima media thickness values. Assessment of atherosclerosis by arterial stiffness measurements represents a valuable diagnostic tool that might reveal a potential role of periodontitis in the earliest stages of atherosclerosis.

periodontitis ; atherosclerosis ; intima-media thickness

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