engleski

Burning Mouth Syndrome-Retrospective Analysis of 328 Patients

Burning mouth syndrome (BMS) is a chronic multifactorial painful condition which primarily affects peril/postmenopausal women. In the published literature there are conflicting data whether local and systemic factors as well as medication intake might contribute to the BMS. The aim of this study was to retrospectively obtain data from the patient charts of 328 BMS patients (270 females and 58 males), median age of the participants was 64 years (age range 17– 88 years)regarding local and systemic disturbances, medication intake and treatment response on the alleviation of oral symptoms. Statistical analysis was performed by use of Chi-square test to assess the differences between categorical variables while Mann Whitney test was used to assess the differences between continuous variables. P values lower than 0.05 were considered significant. Median duration of symptoms was significantly higher in females when compared to males (6 (range 1-180) versus2 (range 1-54) ; p=0.05). No significant differences in age, chief complaint, site, co morbidities, medication intake, and salivary flow rate and treatment outcome between males and females were found. Follow up data were available for 187 patients. One hundred seventeen patients (62.6%) reported their condition to be unchanged while 70 (37.4%) patients reported improvement compared to the baseline. None of the patients reported complete resolution of the symptoms. It may be concluded that there are no associations between burning mouth syndrome with investigated local and systemic diseases and drug intake as well as tried treatment options such as salivary substitutes, low level laser therapy, chlorhexetidine mouthwash and vitamin B1, B6 and B12 replacement therapy.

burning mouth syndrome ; vitamins ; BMS

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