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Cytogenetic damage in exfoliated oral buccal cells by dental composites (CROSBI ID 230532)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Tadin, Antonija ; Galić, Nada ; Marović, Danijela ; Gavic, Lidia ; Klarić, Eva ; Pejda, Slavica ; Ugrin, Klara ; Željezić, Davor Cytogenetic damage in exfoliated oral buccal cells by dental composites // American journal of dentistry, 29 (2016), 4; 219-222

Podaci o odgovornosti

Tadin, Antonija ; Galić, Nada ; Marović, Danijela ; Gavic, Lidia ; Klarić, Eva ; Pejda, Slavica ; Ugrin, Klara ; Željezić, Davor

engleski

Cytogenetic damage in exfoliated oral buccal cells by dental composites

Purpose: To evaluate the possible geno/cytotoxic effects of dental composite materials by assessing the frequency of micronuclei formation and other nuclear abnormalities in the exfoliated buccal epithelium. Methods: Swabs were taken from the buccal mucosa among 85 young healthy subjects. All participants had healthy dentition or dentition restored only with composite materials. Genotoxicity and cytotoxicity was assessed by micronucleus assay. Results: The results indicated no significant difference in number of oral mucosa cells with micronuclei in subjects with different numbers of composite restored tooth surfaces (P=0476). Also, the number of restored surfaces had no effect on nuclear alterations closely related to cytotoxicity, such as karyolysis (P=0.572), karyorrehexis (P=0.573) and picnosis (P=0.765).

genotoxic effects ; cytotoxic effects ; dental composite materials ; micronucleus assay ; buccal mucosa cells

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nije evidentirano

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nije evidentirano

Podaci o izdanju

29 (4)

2016.

219-222

objavljeno

0894-8275

Povezanost rada

Dentalna medicina

Indeksiranost