Vitamin D in osteoporotic patients (CROSBI ID 649511)
Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Pavić, Marina ; Milevoj Kopcinović, Lara
engleski
Vitamin D in osteoporotic patients
Background: Current data demonstrate that an adequate vitamin D status protects bone health by improving bone mineral density and reducing the risk of fracture. The aim of this study was to investigate and compare vitamin D concentrations in patients with osteoporosis divided according to positive history of bone fractures. Methods: Retrospectively, clinical records of 66 adult females with osteoporosis were retrieved from the hospital information system. The study group was divided according to the presence of bone fracture and the concentrations of vitamin D were extracted from our laboratory records. Vitamin D concentrations were determined by electrochemiluminiscent method (ECLIA) on the Elecsys 2010 analyzer (Roche Diagnostics GmbH, Mannheim, Germany). Results: In the whole osteoporosis group aged 71 (26-87) investigated vitamin D concentrations were 50 ± 25 nmol/L and showed no correlation with age (P = 0.503). Recommended vitamin D concentrations (≥ 75 nmol/L) were found in 13% of patients, while insufficient (50-74 nmol/L) and deficient concentrations (< 50 nmol/L) were observed in 29% and 58% of patients, respectively. Osteoporosis patients with fractures (N = 41) had lower concentrations of vitamin D compared to patients without fractures (N = 25), 43 ± 21 nmol/L vs. 61 ± 28 nmol/L, respectively (P = 0.005). Only 27% of patients with osteoporosis and 15% of patients with osteoporotic fractures were receiving vitamin D supplementation therapy. Conclusions: The majority of the osteoporosis patients investigated showed lower vitamin D concentrations than recommended. Deficient vitamin D concentrations were observed in patients with osteoporotic fractures. Adequate vitamin D supplementation is important in the regulation of calcium and phosphorus metabolism, essential for bone health.
vitamin D, osteoporosis
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Podaci o prilogu
S482-S482.
2017.
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objavljeno
Podaci o matičnoj publikaciji
Clinical chemistry and laboratory medicine
Plebani, Mario
Berlin: Walter de Gruyter
1434-6621
Podaci o skupu
22nd IFCC-EFLM European Congress of Clinical Chemistry and Laboratory Medicine - EuroMedLab
poster
11.06.2017-15.06.2017
Atena, Grčka
Povezanost rada
Kliničke medicinske znanosti, Farmacija