engleski

The evaluation of the in vitro antimicrobial properties of fibers functionalized by chitosan nanoparticles

In this work, chitosan (CS) and its water- soluble derivatives, N, N, Ntrimethyl chitosans (TMC) were used in the form of solution and nanoparticles dispersions (CSNP) as an adsorbate for cellulose fibers in order to obtain bioactive functionality of fibers aimed toward tampons use. To examine the usability of bioactive tampons it is extremely important to provide the detailed information about tampons antimicrobial capacity regarding pathogen microorganisms as well as for those responsible for healthy flora such as Lactobacillus sp. Thus, evaluation of the in vitro antimicrobial properties of functionalized fibers was performed in more details using standard Shake- flask test method (ASTM E 2149) and “Time- Kill” method (non-standard method) against S. aureus, E. coli and C. albicans. Both methods were compared. Susceptibility of Lactobacillus sp. to coated fibers was tested as well. Additionally cytotoxic properties of fibers were evaluated as further indicator of safety aspect of tampons functionalized by CS and TMC. The results presented show that specific functionalization of tampons using chitosan nanoparticles could due to the tampon antimicrobial activity and its safety upgrade the regular feminine cotton tampon quality by providing attractive feature.

coatings ; chemistry ; encapsulation ; composites ; materials

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