Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi !

Stereoselective diol production by multi-enzyme system (CROSBI ID 659241)

Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija

Vrsalović Presečki, Ana ; Pintarić, Lela ; Švarc, Anera ; Vasić-Rački, Đurđa Stereoselective diol production by multi-enzyme system // Journal of biotechnology / Dundar, Munis (ur.). 2017. str. S10-S10 doi: 10.1016/j.jbiotec.2017.06.034

Podaci o odgovornosti

Vrsalović Presečki, Ana ; Pintarić, Lela ; Švarc, Anera ; Vasić-Rački, Đurđa

engleski

Stereoselective diol production by multi-enzyme system

Within the field of biocatalysis, multi-enzyme cascade reactions are an important strategy for the production of optically active chemicals. This approach is very promising from an environmental and as well the economical point of view since in this manner higher yields and productivities is accomplished, fewer chemicals are spent, isolation of intermediates is avoided and on industrial scale, waste and production costs are reduced. The synthesis of chiral building blocks is always challenging in the field of organic chemistry, especially the production of molecules with two chiral centers, as the chiral 1, 2-diols. These have wide application as synthons for chemical catalysts, agrochemicals and pharmaceuticals and can be produced by chemical and enzymatic methods. The production of specific form of the stereoisomer of 1, 2-diols by enzymatic approach seems to be more attractive since the synthesis takes place under mild conditions and result with high stereoselectivity. An example of multienzyme catalysis for the production of chiral 1, 2 diol will be presented. By coupling stereoselective carboligation reaction catalyzed by benzoylformate decarboxylase, L- selective reduction of carbonyl group with alcohol dehydrogenase and the coenzyme regeneration by formate dehydrogenase, enantiometrically pure diastereoselective diol was successfully produced from inexpensive substrates.

multi-enzyme cascade reaction, asymmetric reduction, stereoselectivity, alcohol dehydrogenase, benzoylformate decarboxylase

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o prilogu

S10-S10.

2017.

nije evidentirano

objavljeno

10.1016/j.jbiotec.2017.06.034

Podaci o matičnoj publikaciji

Journal of biotechnology

Dundar, Munis

Amsterdam: Elsevier

0168-1656

1873-4863

Podaci o skupu

European Biotechnology Congress 2017

pozvano predavanje

01.01.2017-01.01.2017

Dubrovnik, Hrvatska

Povezanost rada

Kemijsko inženjerstvo, Biotehnologija

Poveznice
Indeksiranost