Does A Single Dose Of Systemic Antibiotic Prevent Postoperative Inflammatory Complications After Lower Third Molar Surgery? A Randomized Controlled Trial (CROSBI ID 256261)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Kotarac Knežević, Ana ; Knežević, Dinko ; Granić, Marko ; Kuna, Tihomir ; Grgić, Nino ; Gabrić, Dragana
hrvatski
Does A Single Dose Of Systemic Antibiotic Prevent Postoperative Inflammatory Complications After Lower Third Molar Surgery? A Randomized Controlled Trial
This study evaluates the effectiveness of a prophylactic single preoperative dose of amoxicillin in decreasing complications after lower third molar surgery. This study consisted of 400 patients indicated for third molar surgery who were randomly divided in two groups (200 patients per group). The first group of patients had never been diagnosed pericoronal inflammation while the second group consisted of patients with preoperative pericoronal inflammation. The both groups were divided in tested and control subgroups (100 patients per group). The tested subgroup received a prophylactic single dose of 2g amoxicillin one hour prior to the procedure. The second control subgroup received a placebo. Complications including swelling, alveolar osteitis, infection, limited mouth opening, pain, bleeding, and increased body temperature were evaluated postoperatively. The results of placebo subgroup within the first group were: a more statistically significant first degree swelling within 24 hours (P=0.048). The results of placebo subgroup within the second group were: pain intensity after seven days was significantly more intense (P=0.001) and the average duration of pain was significantly longer. Prophylactic dose of amoxicillin have a benefical effect on postoperative complications and can be recommended as a routine method in healthy patients with previous inflammation.
umnjak ; intraoralni operativni zahvati ; postoperativne komplikacije ; antibiotska profilaksa ; placebo učinak
nije evidentirano
engleski
Does A Single Dose Of Systemic Antibiotic Prevent Postoperative Inflammatory Complications After Lower Third Molar Surgery? A Randomized Controlled Trial
nije evidentirano
third molar ; oral surgical procedures ; postoperative complications ; antibiotic prophylaxis ; placebo effect
nije evidentirano
Podaci o izdanju
9 (6)
2018.
1223-1233
objavljeno
0975-8585
Trošak objave rada u otvorenom pristupu
Povezanost rada
Dentalna medicina