Synthesis of Novel Ureido and Hydroxamic Derivatives of Coumarin[4, 3-c]thiophene (CROSBI ID 589908)
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Podaci o odgovornosti
Benci, Krešimir ; Mandić, Leo ; Suhina, Tomislav ; Wittine, Karlo ; Mintas, Mladen
engleski
Synthesis of Novel Ureido and Hydroxamic Derivatives of Coumarin[4, 3-c]thiophene
Aromatic urea derivatives have been widely used for cancer patients with great clinical success and are continuing to be important chemotherapeutic agents. This class of compounds has been proven to be tubulin ligands that inhibit the polymerization of tubulin. We synthesized a series of novel ureido (6b–10b) and hydroxamic (12b– 13b) derivatives of coumarin[4, 3-c]thiophene for their antitumor and antiviral activity evaluation.
Ureido and Hydroxamic Derivatives of Coumarin[4; 3-c]thiophene
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Podaci o prilogu
379-379.
2012.
objavljeno
Podaci o matičnoj publikaciji
Podaci o skupu
Povezanost rada
Kemija
