engleski

Mathematical modeling of metal ions removal in the horizontal rotating tubular bioreactor

In this work, the bioadsorption process was studied in a pilot scale horizontal rotating tubular bioreactor (HRTB). On the basis of the results obtained via inductively coupled plasma sector field mass spectrometry an integrated mathematical model of heavy metal removal (Co2+, Cr6+ and Mn2+) in HRTB was established. It combines hydrodynamics (mixing) and kinetics in order to define bioprocess conduction in the bioreactor. Mixing in HRTB was described by a structured cascade model and metal ion removal by a combined diffusion-bioadsorption model, respectively. Differences between experimental and simulated metal ion concentrations were in the range of the experimental uncertainty, demonstrating that the established bioprocess model successfully predicts metal ion concentrations in HRTB over a wide range of process parameters [rotation speed (n = 5 - 30 min-1) and inflow rate (F = 0.5 - 2.0 L h-1)]. Furthermore, the obtained results also pointed out that the established model is accurate and robust and has therefore a high potential for use in a scale-up procedure.

mathematical modeling; horizontal rotating tubular bioreactor

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